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| Extension | Information |
| CDKEY | Protocol Used in Communicating from MediaRemote Server to PC MediaRemote Plug-in |
| CDL | CADKEY Advanced Design Language (CADL) (CADKEY) CaseWare Working Papers Document Link SignLab Vector Graphic |
| CDM | Compressed Music Format Novell NetWare Disk Drivers NPA PowerDesigner Conceptual Model File Visual dBASE Custom Data Module |
| CDO | Cdo Navigator CADAM Overlay (Dassault Systemes) |
| CDP | CD/Spectrum Pro |
| CDPRJ | CD Menu Creator Project File (Drackon Tech) |
| CDQ | CD Indexer |
| CDR | Corel Vector Graphic Drawing (Corel) Raw Audio-CD Data Sound File Elite Plus Commander Saved Game GameJack Virtual CD or DVD Image (S.A.D. GmbH.) |
| CDS | ChemDraw Stationery Document Delphi TClientDataset Data (Borland Software Corporation) |
| CDT | Corel Draw Template ProWORX Nxt Temporary Long Comment Data (Schneider Electric) STABCAL (stability calculation for aqueous systems) File |
| CDU | CDU Paint |
| CDV | CatDV Media Catalog (Square Box Systems Ltd.) |
| CDW | CADKEY Organized Dialog File (CADKEY) CeledyDraw Image |
| CDX | Active Server Document ChemDraw Chemical Structure Compound Index Corel Draw Compressed Drawing Microstation Cell Library Index Visual Foxpro Index (Microsoft) NovaBACKUP Backup Database Index (NovaStor Corporation) Alpha Five Table Index (Alpha Software) |
| CDXL | Old Amiga Movie Format |
| CDXML | ChemDraw XML ChemDraw Format |
| CDZ | ROM With a View Project File |
| CE | CA Clipper Workbench Application Computer Eyes, Digital Vision FarSide Computer Calendar File |